When C# comes out I'll probably be knee deep in MW5, so it might be a while before I do anything. But my first game I think I'd do a semi-authoritarian government bent on 'oversight' of the surrounding space lanes of any human populated world. Purely for the preservation of humanity of course. To do this, I'm envisioning big battlewagons fit with layered energy defenses (longest range particle beams, biggest bore plasma, and fastest firing rail), with each ship sporting a decent amount of 'unreloadable' missile launchers (probably .33x or .25x size). Each ship would be fairly independent, with the caveat of FACs, while each world is responsible for it's own small task force (probably only 1-2 mainline warships and a handful of escorts) while the main fleets are stationed at bases set up at key junctions in the lanes. Probably will make extensive use of minefields (since seeding asteroids with PDFs would presumably no longer be a thing).