The early tech stuff is real, for instance as I recall modern nuclear warheads are fusion boosted fission (5 per MSP), which is a two stage thermonuclear weapon. The higher techs are theoretical, for instance the tri cobalt tech is from star trek, which in turn was based on a theory from the cold war about a so called 'cobalt' salted nuclear weapon.
Power techs are similar, most nuclear power plants in operation are third generation pressurised light water reactors, fast breeder reactors (gas cooled?) are used for making plutonium for nuclear weapons programs but there aren't many in operation, other techs there are experimental, such as pebble bed reactors, or the fusion types which there are many kinds being experimented on such as tokamak, stellarator, magneto inertial fusion, etc before going into science fiction again with techs like Antimatter and vacuum energy, which are theoreically possible but not really.
Then propulsion is similar with experiments being done in the 50's or 60s with nuclear thermal fusion, nuclear pulse fusion was worked on with the idea of dropping coke can sized bombs out of a dispenser designed by coke vending machine experts (no joke) and launching a spacecraft sitting on top of a thick steel plate. Project orion as already mentioned.
Ion and magneto plasma are real technologies that are actually used for spacecraft, they produce a hell of a lot of delta V (change in velocity) for a tiny amount of fuel, but require immense power, either nuclear or solar power, solar power is bulky so generally these techs are used for a miniscule amount of power which is used over a very long period to get anywhere.
Then once again you get into sci fi terms.
Finally the trans newtonian minerals are loaded with science fiction, the majority of them (maybe all?) are even the original series of star trek, like Duranium, Corbomite, Neutronium (common in scifi, an atom made entirely out of neutrons), Gallicite, Sorium, Vendarite etc.