Well, being able to roleplay a Homeworld style civilisation is nice.
Buut, we kinda need space-borne factories and shipyards, to make it like a nomadic space travellers experience.
Also, are they really that vulnerable, if they carry a whole fleet with them?
And, considering that you kind of need to use military hangars... Or were you planning on commercial hangars?
Right now, the fairly logical option in game is to establish a base near a combat zone for resupply and refuel. And, a simple small asteroid is pretty much enough for that. Mostly.
So, impractical with current gameplay rules, but could be fun...
Homeworld however does not deal with TN materials, just RUs - Resource Units - and storage space... So, even if space-borne factories and shipyards were implemented, we have storage space problems...