If your looking to actually crack the planet, kinetic is probably the way to go, but it would have to be big and fast.
If your just looking at icing a city, or disposing of obnoxious biologicals, then nukes/radiological weapons are the way to go. Its faster, cheaper, and from a strategic perspective a much easier weapon that say a tailor made biological weapon. They also don't tend to mutate like a biological might.
Cobalt bombs for example, are intensely radioactive, but the half like only around 5 years. If you don't like waiting that long, there are other types of radiological/nuclear fallout weapons that have even shorter durations.
Sodium-24: 15 hours
Gold-198: 3 days
Tantalum-182: 115 days
Zinc-65, 245 days
Of course those half lives are only for the isotopic materials, and are generated by a regular nuke, which is going to leave a LOT of regular radioactive contamination around. In theory, these isotopic nukes were small yield but intensely radioactive for short durations. Kill the bad guys and then roll into town a week later, is more less what they were designed for. Nobody has actually BUILT one, but the theory is there.
From a game perspective though, it might be a bit too much like GFFP. Also, some aren't exactly practical. Sodium has unpleasant reactive qualities that make it challenging to handle, and gold is a bit too pricey to be lobbing it around in mass produced nuclear weapons.
The other problem is that while the intense gamma ray emitters die off fairly quickly, the remaining isotopes from the blast are still present and due to the decreased yield and blast radius, could be possibly more concentrated in a smaller area.
You COULD use the current genetics research tree do do a biological warhead, and the idea has gotten used in a couple of games (thinking Sword of the Stars in particular) but the RESEARCH costs and time to do a tailor made bio-weapon for an alien race you dont have much info on is going to be huge.
Once again, you start getting into GFFP, which Steve hasnt been really thrilled about in the past, and the other problem, is that if the NPR's get to use them like players, they WILL use them. Unless of course Steve feels inclined to do a lot of AI coding to factor in racial militancy or xenophobia before the NPR gets weapons release for the bad stuff....
Either way,