Two consecutive companies was killed with CycleOrders error (something with changing data type in description).
Actually you can't even resolve it with kill->reload, it's starts right upon you advancing in time and cycles forever.
It's even corrupted mdb once, but i've managed to repair it.
It's really annoying, because it's seems to be game over and getting it twice in a row is heartbreaking

Edit.
Seems like I figured it out. It's was gazillion of records in FleetOrders table. My cargo ship was trying to infinitely populate conditional order "to refuel at 20% at nearest Colony or Tanker". I deleted all records and game now seems work fine.
But my cargo ship was a tanker itself, so probably it's caused infinite loop. Seems like my previous game suffered to the same isssue.