I'm currently playing a game with Conventional Industry (using 5.14).
I started the game with 2000 systems and Precursors turned off, so that any NPR races would have less of a chance to find me, and the nasty wormhole aliens wouldn't pop through to wipe me out.
I had 1 billion starting pop and the normal number of research colonies, and added a zero to the end of all minerals (putting them in the 100,000 range), except for duranium which was already in the 100,000 range, so I doubled it. I also put 2 ruins in system, to give humans the idea that they weren't alone.
I'm almost 25 years in, and am over 10 years from running out of my lowest mineral. I was also fortunate enough to have minerals in the millions on Venus and TItan, almost so I don't have to go out system. However I'm going to soon, my first jump ship will be ready in about a year.
I really like the civilian sector now - they turned smart! I'm colonizing Titan, and now the civilians wait until there's enough infrastructure to plop their 50,000 colonists down, instead of sending them to their deaths.