Antonin, you should build harvester/tanker ships with rather large tanks, i.e. 1 million or more litres capacity.
Together with commercial engines, consuming very, very low fuel, you can easily go from Earth to Saturn, or even more distant, with 10% or a bit less fuel left in the tanks when you leave the Earth.
Otherwise, you are producing fuel just to move back and forth the tanker.
I created a new harvester design, setting a fuel reserve level of 200,000 L in the class design window. I built a ship, with "Primary Condition/Conditional Order = Harvester Transfer and Return." Then I gave it a movement order "Jupiter--->Move to Location." Then I clicked "Add Move."
I advanced the game 5 days, but the ship is still in Earth orbit, with 2 mil L of fuel in its tank.
I'm still doing *something* wrong, I guess.
My new harvester design:
Gobi class Fuel Harvester 74,522 tons 309 Crew 941.3 BP TCS 1,490 TH 672 EM 0
450 km/s Armour 1-157 Shields 0-0 HTK 113 Sensors 0/0/0/0 DCR 1 PPV 0
MSP 7 Max Repair 50 MSP
Cargo 25,000 Cargo Shuttle Multiplier 6
Lieutenant Commander Control Rating 1 BRG
Intended Deployment Time: 3 months
Fuel Harvester: 12 modules producing 480,000 litres per annum
Commercial Nuclear Pulse Engine EP168.00 (4) Power 672 Fuel Use 2.66% Signature 168 Explosion 3%
Fuel Capacity 2,000,000 Litres Range 181.1 billion km (4657 days at full power)
Refuelling Capability: 60,000 litres per hour Complete Refuel 33 hours
This design is classed as a Commercial Vessel for maintenance purposes
This design is classed as a i for auto-assignment purposes